SAMe (S-adenosyl-methionine) is an amino acid derivative normally synthesized in the body. SAMe is used by the body in three important pathways: Methylation (contributing methyl groups to activate certain molecules)16,17 The synthesis of polyamines (for cell growth, gene expression, neuronal regeneration, etc.)18-20 Trans-sulfuration (synthesis of cysteine, glutathione, and other sulfate chemicals)21-23 SAMe occurs naturally in… Continue Reading